The manufacturing sector is undergoing a paradigm shift driven by hyper-connectivity, sustainability imperatives, and accelerated digital transformation. Conventional systems, however, remain constrained by their focus on isolated optimizations—such as predictive analytics, IoT-enabled sensing, or workforce scheduling—without providing an integrated operational perspective. To address this fragmentation, Nexifi11D is introduced as a comprehensive, multidimensional framework that consolidates 11 critical dimensions of manufacturing into a unified ecosystem. Nexifi11D advances beyond traditional Industry 4.0 architectures by seamlessly integrating intelligent algorithms, immersive simulation technologies, IoT infrastructure, and predictive systems within a scalable, interoperable mesh. The framework breaks down silos across key manufacturing domains—such as sustainability, cost, operations, and workforce—enabling holistic, data-driven, and proactive decision-making. Each integrated