The decarbonization of the transport sector has become a priority for governmental authorities and industrial stakeholders alike, driving regulatory measures and innovation in powertrain technologies. Among the innovative solutions, hydrogen combustion engines have gained significant attention due to their customization to diverse applications, including heavy-duty vehicles, passenger cars, generators, and even two- and three-wheelers. Hydrogen combustion, characterized by high ignitability, rapid flame speed, soot-free operation, and water as a combustion by-product, introduces distinct challenges for engine lubrication. These unique characteristics require the development and adaptation of lubricant formulations to ensure optimal engine performance and durability. Specifically, tailored lubricants play a vital role in addressing four key challenges: pre-ignition, particulate emissions, water contamination, and wear protection. This study investigates the impact of crucial formulation