Browse Topic: Medical, health, and wellness
Biomanufacturing uses microorganisms to produce chemicals or materials of interest, much like a brewery uses fermentation by yeast to produce the alcohol in beer. Biomanufacturing relies upon synthetic biology to reprogram yeast or other microorganisms to produce something of greater value, such as fuel, food, or pharmaceuticals. Industrial biomanufacturing has made significant advances and the products it can deliver include reactive coatings and textiles, sensors, optical materials that can bend light, and new therapeutics such as antimicrobials and vaccines. The convergence of synthetic biology, robotics, and artificial intelligence is opening the way to produce materials never before possible in the commercial market. These same technologies create the opportunity for the miniaturization of this technology to fit into ever more compact spaces, bringing forward deployment of these mini-factories closer and closer to the point of need.
Modern mission-critical ground vehicle systems must adapt to rapidly evolving threats, deploying changes in months or days while maintaining reliable and safe operation. Historic manual development and testing methods cannot keep pace without compromising safety assurances. Continuous Integration and Continuous Deployment (CI/CD) pipelines offer proven approaches to accelerating development, but implementing them for mission-critical systems requires careful attention to verification rigor. This paper presents a practical framework for implementing CI/CD pipelines across any level of rigor, from rapid prototyping to DO-178C and ISO 26262 certified systems. Drawing on experience from aviation, medical device, and ground vehicle development, the framework provides guidance for each pipeline stage based on the system’s desired level of rigor. This framework includes an examination of the value of Software-in-the-Loop vs Hardware-in-the-Loop testing to optimize development timelines while maintaining software quality.
Military ground vehicles are transitioning from manually operated platforms to highly automated systems, which fundamentally alters the cognitive demands placed on crew members. Rather than reducing workload, automation frequently redistributes it, introducing challenges associated with supervisory monitoring, autonomy mode calibration, and situational awareness. Augmented cognition (AugCog) offers a closed-loop framework in which real-time physiological and behavioral measures of operator cognitive state can be used to dynamically adapt system interfaces and autonomy levels. This paper reviews six nonintrusive sensor modalities suitable for military ground vehicle crew stations: remote photoplethysmography (rPPG), facial thermography, eye tracking and pupillometry, dry-electrode electroencephalography (EEG), Facial Action Coding System (FACS) action unit (AU) analysis, and elastic electrodermal activity (EDA) sensors. A conceptual multimodal crew station integration framework is proposed, and future research directions are outlined.
Every kid who has read a comic book or watched a Spider-Man movie has tried to imagine what it would be like to shoot a web from their wrist, fly over streets, and pin down villains. Researchers at Tufts University took those imaginary scenes seriously and created the first web-slinging technology in which a fluid material can shoot from a needle, immediately solidify as a string, and adhere to and lift objects.
Spinoff is NASA’s annual publication featuring successfully commercialized NASA technology. This commercialization has contributed to the development of products and services in the fields of health and medicine, consumer goods, transportation, public safety, computer technology, and environmental resources.
Researchers at the University of California, Irvine, and New York’s Columbia University have embedded transistors in a soft, conformable material to create a biocompatible sensor implant that monitors neurological functions through successive phases of a patient’s development.
Researchers at Cornell University, working with collaborators, have created an extremely small neural implant that can sit on a grain of salt. Despite its size, the device can wirelessly transmit brain activity data from a living animal for more than a year.
Using an inexpensive electrode coated with DNA, MIT researchers have designed disposable diagnostics that could be adapted to detect a variety of diseases, including cancer or infectious diseases such as influenza and HIV.
A sweat-powered wearable has the potential to make continuous, personalized health monitoring as effortless as wearing a Band-Aid. Engineers at the University of California San Diego have developed an electronic finger wrap that monitors vital chemical levels — such as glucose, vitamins, and even drugs — present in the same fingertip sweat from which it derives its energy.
Smart implants that not only stabilize a fracture but also monitor the healing process from day one — and deliver targeted support when required — are currently being developed at Saarland University by a team of engineers, medical researchers, and computer scientists. The engineering team led by Paul Motzki is contributing shape-memory micro-actuators with integrated sensing capabilities, while Bergita Ganse and her research group provide the medical expertise in fracture healing.
Surgical face masks help prevent the spread of airborne pathogens and therefore were ubiquitous during the COVID-19 pandemic. Now, a modified mask could also protect a wearer by detecting health conditions, including chronic kidney disease. Researchers reporting in ACS Sensors incorporated a specialized breath sensor within the fabric of a face mask to detect metabolites associated with the disease. In initial tests, the sensor correctly identified people with the condition most of the time.
Materials innovations are shaping the next generation of medical devices. In this Q&A, Jeremy Schaffer, director of research and development at Fort Wayne Metals, discusses how advances in titanium, nickel-titanium, surface engineering, and smart materials are helping device developers improve performance, miniaturization, durability, and patient outcomes. He also addresses sustainability, scale-up challenges, and the collaborations needed to move promising materials from research into real-world medical use.
Ultra-miniature sensors are enabling advanced procedures and treatments across a wide range of medical devices, from catheters and neuro interfaces to wearables. But as electromagnetic sensors get smaller, trade-offs begin to emerge — lower sensitivity, less tolerance for environmental influences, and greater susceptibility to interference — underscoring the need for robust testing to ensure accurate, reliable tracking.
Medical imaging technology is advancing rapidly, bringing new opportunities and challenges for machine designers. Systems that once required dedicated hospital rooms and significant floor space are becoming more compact, faster, mobile and capable of delivering increasingly detailed clinical insight. From advanced CT scanners to imaging platforms integrated with surgical robotics, imaging equipment is evolving toward more point-of-care (POC) solutions to meet rising expectations for diagnostic accuracy, procedural guidance and operational efficiency.
This study evaluates whether a statewide layered medical-drone architecture can improve time-critical EMS logistics in Florida by delivering blood products, AEDs, and critical support devices. We define Time-To-Clinical-Support (TTCS) as the interval from incident recognition to first effective therapy and use Florida EMS benchmark intervals, county-level population and centroid distance data, and p-median hub placement to model system performance. Scenario analysis compares 20-, 40-, and 60-hub deployments and estimates order-of-magnitude effects on AED TTCS and survival gains under explicit assumptions for availability, cruise speed, dispatch overhead, and bystander uptake. The results indicate that a mid-scale network may reduce delay sufficiently to produce meaningful clinical benefit, provided it is integrated with EMS dispatch, medical direction, cold-chain controls, and hurricane-resilient infrastructure. Regulatory pathway constraints, incomplete county-level OHCA data, and uncertainty in mission availability remain the primary limitations on precision and external validity.
This paper investigates the use of full-body vibrotactile cueing to augment operator perception during swarm teleoperation tasks. Piloted simulations are conducted in a virtual reality (VR) flight simulation environment using a quadcopter swarm model and a nonlinear dynamic inversion (NDI) flight control architecture. A scaled version of the ADS-33 slalom Mission Task Element (MTE) is implemented to evaluate swarm formation maintenance and obstacle avoidance under four experimental conditions: Good Visual Environment (GVE), Degraded Visual Environment (DVE), and each of these conditions augmented with haptic feedback. Haptic cues are delivered through vibrotactile vests and sleeves to convey information on formation deformation and gate proximity. Experimental results involving human participants indicate that haptic feedback improves formation maintenance and increases operators’ situational awareness of follower drone positions without increasing perceived mental workload. While haptic cues provided modest assistance in gate localization, visual conditions remained the dominant factor influencing obstacle avoidance performance. Overall, the results indicate that full-body haptic feedback provides an effective modality for augmenting operator perception and supporting swarm supervision tasks, particularly in visually degraded environments.
In response to the 42nd (2025) Annual VFS Student Design Competition, the Graduate Student Design Team from the University of Maryland introduces Wyvern, a novel hydrogen-powered electric compound rotor-craft engineered for maximum loiter and operational safety. Named after a mythical dragon that defies convention by not breathing fire, Wyvern only breathes water vapor by forgoing hydrocarbon combustion in favor of the quiet and clean power of hydrogen. This design reflects not only an aeronautical solution to an engineering challenge but a greater aspiration to reshaping how practical and clean vertical flight can be achieved.
Rotorcraft pilots operating in degraded visual environments encounter significant challenges during hover flight, where the absence of critical visual cues increases the risk of spatial disorientation. At low altitudes and in obstacle-rich environments, even minor losses in situational awareness can have severe consequences. Understanding the visual cues that support stable hover in good visual environments, and how their absence impacts performance and cognitive workload, is essential for mitigating these risks. This study examined key human factors in hover flight, focusing on the role of peripheral vision and microtextures in supporting pilot performance. It evaluated whether naturally relied-upon visual cues in good visual environment conditions can be artificially replicated to restore visual dominance in simulated degraded visual environments. Analysis included flight performance metrics, control inputs, physiological workload indicators, subjective assessments, and pilot feedback. The findings contribute to improved understanding of visual cueing and pilot adaptation in degraded conditions.
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