Browse Topic: Cardiovascular system

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In the quest to develop lifelike materials to replace and repair human body parts, scientists face a formidable challenge: Real tissues are often both strong and stretchable and vary in shape and size
University of Waterloo Chemical Engineering Researcher Dr. Elisabeth Prince teamed up with researchers from the University of Toronto and Duke University to design the synthetic material made using cellulose nanocrystals, which are derived from wood pulp. The material is engineered to replicate the fibrous nanostructures and properties of human tissues, thereby recreating its unique biomechanical properties
In recent times, indoor air quality has become an important concern as it affects people’s health and comfort. According to WHO report, air pollution causes 7 million deaths every year. PM2.5 has been identified as a key pollutant which impacts human health causing diseases like stroke, heart diseases, breathing issues, cancer and so on [1]. In today's time, we travel by personal vehicle every day, commuting for hours. It is an extension to our homes. Unfortunately, due to frequent door and windows opening, the cabin air gets exposed to outside pollution, and we end up breathing pollutants. To mitigate the problem, air purifiers are added in the automobile. As people are becoming more aware and conscious about good air quality, there is a growing demand for cabin interior air quality solutions for automobiles. A popular approach is to add an air purifier inside cars like ones being used in our homes to bring down the PM2.5 levels. The air purifier consists of a filter, blower system
Pimpalkar, AnkitPatel, AbhishekSonkar, SurabhiRajaur, DeepakJoshi, Rishi
A wearable health monitor can reliably measure levels of important biochemicals in sweat during physical exercise. The 3D-printed monitor could someday provide a simple and non-invasive way to track health conditions and diagnose common diseases, such as diabetes, gout, kidney disease or heart disease
For many patients waiting for a donor heart, the only way to live a decent life is with the help of a pump attached directly to their heart. This pump requires about as much power as a TV, which it draws from an external battery via a seven-millimeter-thick cable. The system is handy and reliable, but it has one big flaw: despite medical treatment, the point at which the cable exits the abdomen can be breached by bacteria
Understanding heart function and disease, as well as testing new drugs for heart conditions, has long been a complex and time-consuming task. A promising way to study disease and test new drugs is to use cellular and engineered tissue models in a dish, but existing methods to study heart cell contraction and calcium handling require a good deal of manual work, are prone to errors, and need expensive specialized equipment
Investigating human driver behavior enhances the acceptance of the autonomous driving and increases road safety in heterogeneous environments with human-operated and autonomous vehicles. The previously established driver fingerprint model, focuses on the classification of driving styles based on CAN bus signals. However, driving styles are inherently complex and influenced by multiple factors, including changing driving environments and driver states. To comprehensively create a driver profile, an in-car measurement system based on the Driver-Driven vehicle-Driving environment (3D) framework is developed. The measurement system records emotional and physiological signals from the driver, including the ECG signal and heart rate. A Raspberry Pi camera is utilized on the dashboard to capture the driver's facial expressions and a trained convolutional neural network (CNN) recognizes emotion. To conduct unobtrusive ECG measurements, an ECG sensor is integrated into the steering wheel
Ji, DejieFlormann, MaximilianWarnecke, Joana M.Henze, RomanDeserno, Thomas M.
Researchers from North Carolina State University have developed an exosome-coated stent with a “smart-release” trigger that could both prevent reopened blood vessels from narrowing and deliver regenerative stem cell-derived therapy to blood-starved, or ischemic, tissue
The global medical device market offers opportunities for innovation-driven growth. Demand for smart, new lifesaving and life-enhancing technologies is perhaps stronger than ever. Manufacturers around the world looking to capitalize on this eager global market face a long list of challenges — some big, some small. Supply-chain disruptions, labor shortages, rising materials costs, and other headwinds are leading to delays in both engineering and manufacturing processes. Despite these challenges, the world demands medical device manufacturers’ best. A surging geriatric population, implications of a global pandemic, and the mortality rates for heart disease, cancer, obesity, and other conditions are all contributing to strong and sustained market demand. One study predicts a compound annual growth (CAGR) of 5.4 percent will push global sales of medical devices to nearly $658 billion (USD) by 2028. Of course, the road to success will be littered with familiar roadblocks — and some that are
iMotions employs neuroscience and AI-powered analysis tools to enhance the tracking, assessment and design of human-machine interfaces inside vehicles. The advancement of vehicles with enhanced safety and infotainment features has made evaluating human-machine interfaces (HMI) in modern commercial and industrial vehicles crucial. Drivers face a steep learning curve due to the complexities of these new technologies. Additionally, the interaction with advanced driver-assistance systems (ADAS) increases concerns about cognitive impact and driver distraction in both passenger and commercial vehicles. As vehicles incorporate more automation, many clients are turning to biosensor technology to monitor drivers' attention and the effects of various systems and interfaces. Utilizing neuroscientific principles and AI, data from eye-tracking, facial expressions and heart rate are informing more effective system and interface design strategies. This approach ensures that automation advancements
Nguyen, Nam
As medical devices in today’s modern medicine continue to advance, they require power supplies that allow them to perform an ever-widening roles. These lightweight, wearable — and even implantable — medical devices comprise everything from activity/exercise watches, hearing aids, and medical call buttons to pacemakers, insulin pump monitors, and neuro- or gastric stimulators, as well as implantable cardiac pacemakers and defibrillators (ICDs). The rechargeable batteries used in these devices must provide for such vital functions as monitoring, signal processing, collecting and transmitting data, and providing specialized electronic pulses when needed to stimulate cardiac output and other physiological activity
With the rapid development of intelligent driving technology, there has been a growing interest in the driving comfort of automated vehicles. As vehicles become more automated, the role of the driver shifts from actively engaging in driving tasks to that of a passenger. Consequently, the study of the passenger experience in automated driving vehicles has emerged as a significant research area. In order to examine the impact of automatic driving on passengers' riding experience in vehicle platooning scenarios, this study conducted real vehicle experiments involving six participants. The study assessed the subjective perception scores, eye movement, and electrocardiogram (ECG) signals of passengers seated in the front passenger seat under various vehicle speeds, distances, and driving modes. The results of the statistical analysis indicate that vehicle speed has the most substantial influence on passenger perception. The driving mode has a minor effect on the passenger riding experience
Hu, HongyuZhang, GuojuanCheng, MingLi, ZhengyiHe, LeiSu, Lili
Researchers have been pursuing the development of robots so tiny that they can maneuver through blood vessels and deliver medications to certain points in the body. Now, scientists have succeeded in building such micromachines out of metal and plastic in which these two materials are interlocked as closely as links in a chain. This is possible thanks to a new manufacturing technique they have devised
ECGs help manage cardiovascular disease — which affects around 4 million Australians and kills more than 100 people every day — by alerting users to seek medical care
Monitoring the success of surgery on blood vessels is challenging, as the first sign of trouble often comes too late. By that time, the patient often needs additional surgery that carries risks similar to the original procedure. A new device could make it easier for doctors to monitor the success of blood vessel surgery
A beating heart makes for a formidable surgical arena, but a new robotic catheter could someday equip surgeons to operate in the cardiac environment with greater ease
Royal Philips is integrating AI in its cardiac ultrasound devices and across cardiac care to help improve clinical confidence and increase efficiency. The portable Philips Ultrasound Compact System 5500 CV includes an AI-powered automation tool (the automated strain quantification) to assess the function of the heart’s left ventricle, a key indicator of heart health
In patients with severe artery blockage in the lower leg, an artery-supporting device called a resorbable scaffold is superior to angioplasty, which has been the standard treatment. A resorbable scaffold is a stent-like structure that props the artery open but is biodegradable and dissolves within a few years, avoiding some of the potential complications of a permanent stent
Researchers from MIT Lincoln Laboratory and their collaborators at the Massachusetts General Hospital (MGH) Center for Ultrasound Research and Translation (CURT) have developed a new medical imaging device: the Noncontact Laser Ultrasound (NCLUS). This laser-based ultrasound system provides images of interior body features such as organs, fat, muscle, tendons, and blood vessels. The system also measures bone strength and may have the potential to track disease stages over time
For some with AFib, a catheter ablation is used to burn or freeze the precise area causing the problem to restore a normal heart rhythm. While this method is effective, the energy from the catheter tip can cause serious damage to the adjacent esophagus, which is only a few millimeters away. It’s an injury that can be life threatening, so an electrophysiologist has helped develop a new device that gently diverts the esophagus out of harm’s way, greatly improving safety
Our brains contain an intricate network of arteries that carry blood throughout the organ along winding paths. For neurosurgeons, following these paths with a wire — which is just a third of a millimeter in diameter and enters the body through the femoral artery — to reach an obstructed blood vessel can be tricky. For instance, if they want to point the wire in a different direction, they often have to pull the instrument out and then reinsert it, lengthening surgery times and increasing the risk of complications
Nearly 700,000 people in the United States die from heart disease every year, and one-third of those deaths result from complications in the first weeks or months following a traumatic heart-related event
Strep throat is a common and treatable childhood disease in the United States, but in less wealthy countries, children afflicted with strep can develop rheumatic fever, in which runaway inflammation attacks the body’s tissues. Rheumatic fever often damages the valves of the heart, causing rheumatic heart disease that can lead to serious health problems, including heart failure
Engineers at the University of California San Diego developed a soft and stretchy ultrasound patch that can be worn on the skin to monitor blood flow through major arteries and veins deep inside a person’s body
Huge libraries of drug compounds may hold potential treatments for a variety of diseases, such as cancer or heart disease. Ideally, scientists would like to experimentally test each of these compounds against all possible targets but doing that kind of screen is prohibitively time consuming
Therapy developers are being asked to consider ways to deliver drugs for a longer time period with a single dose. This has spurred innovation in both the oral and parenteral spaces, but the greatest potential for long-acting delivery remains in implantable systems. Because of this, growth for the global implantable drug-delivery market is forecast at 10 percent annually in coming years with an expectation for the market to reach nearly $30 billion (USD) by 2025.1 Contraceptive, ophthalmic, cardiovascular, diabetes, oncology, and autoimmune disease applications are all likely to focus on development of these therapeutic forms
Creaking joints come from cartilage rubbing on other soft tissue. A growling stomach signals hunger or that you’ve eaten something that disagrees with you. And though a cough can mean that you are ill, you might also be perfectly healthy and just took too big of a gulp of your drink. Even more interesting is that our body sounds and its variation over time could tell us a lot not only about a particular organ (e.g., your knee cartilage and tendons), but also about general wellness, and respiratory, cardiovascular, digestive, and neurological health. This article digs into the future of acoustic epidemiology and our growing ability to interpret the body’s sounds using artificial intelligence (AI
A new technology that uses bioprinted patches to repair damaged heart tissue has been proven to be safe and cost-effective for patients
A University of California San Diego-led team has developed a wearable ultrasound device — about the size of a postage stamp — that can assess both the structure and function of the human heart. The portable device can be worn for up to 24 consecutive hours and works even during strenuous exercise
Researchers have created an engineered heart via 3D printing technology that allows for early monitoring of drug-induced cardiotoxicity. They produced the heart model using biohybrid 3D printing
A new sensor — so cheap and simple to produce that it can be hand-drawn with a pencil onto paper treated with sodium chloride — could clear the way for wearable, self-powered health monitors for use not only in “smart diapers” but also to predict major health concerns like cardiac arrest and pneumonia
Monitoring driver thermal stress is an integral step for developing an automated climate control function. In this experimental study, various physiological measures for driver’s thermal stress were tracked while intentionally by altering thermal conditions of the seat with a seat air conditioning system (ACS) in summer and a seat heating system (HS) in winter. It was aimed to determine reliable physiological measures for identifying the changes in thermal status induced by the two seat climate control systems. In the first experiment, twenty experienced drivers drove a comfortable sedan for 60 minutes on a real highway while varying the intensity of the seat ACS every 10 minutes to incur ‘hot’ – ‘cool’ – ‘hot’ – ‘cool’ thermal stress. In the second experiment, a new group of eighteen drivers drove the same highway for 30 minutes while increasing the intensity of seat HS to incur ‘cold’ to ‘warm’ thermal stress. Their thermal stress status has been evaluated by heart rate variability
Song, DonghyunKim, EunjeeKwon, YujinYoon, WoojinLee, BaekheeLee, YoseobShin, Gwanseob
A new biomaterial that can be injected intravenously, reduces inflammation in tissue and promotes cell and tissue repair. The injectable biomaterial was tested and proven effective in treating tissue damage caused by heart attacks in both rodent and large animal models. Researchers also provided proof of concept in a rodent model that the biomaterial could be beneficial to patients with traumatic brain injury and pulmonary arterial hypertension
Engineers and physicians have developed a wearable ultrasound device that can assess both the structure and function of the human heart. The portable device, which is roughly the size of a postage stamp, can be worn for up to 24 hours and works even during strenuous exercise
A new sensor could help workers in daycares, hospitals, and other settings provide more immediate care to their charges. The new sensor — so cheap and simple to produce that it can be hand drawn with a pencil onto paper treated with sodium chloride — could clear the way for wearable, self-powered health monitors for use not only in “smart diapers” but also to predict major health concerns like cardiac arrest and pneumonia
With cancer, diabetes, and heart disease among the leading causes of disability and death in the United States, imagine a long-term, in-home monitoring solution that could detect these chronic diseases early and lead to timely interventions
A highly sensitive wearable sensor for cardiorespiratory monitoring could potentially be worn continuously by cardiac patients or others who require constant monitoring
Cardiovascular diseases account for 32 percent of global deaths. Myocardial infarction, or heart attacks, play a large part in heart diseases and the necrosis of cardiac tissue after blood supply is decreased or stopped
There are about 64 million cases of heart failure worldwide. According to the American Heart Association, 6.2 million adults in the United States have heart failure and that number is estimated to increase to 8 million by 2030. Heart failure is a progressive clinical syndrome characterized by a structural abnormality of the heart, in which the heart is unable to pump sufficient blood to meet the body’s requirements
Using a suspended nanowire, a University of Massachusetts research team has created a tiny sensor that can simultaneously measure electrical and mechanical cellular responses in cardiac tissue — a first
Implantable bioelectronics are now often key in assisting or monitoring the heart, brain, and other vital organs, but they often lack a safe, reliable way of transmitting their data to doctors. Now researchers at Columbia Engineering have invented a way to augment implantable bioelectronics with simple, high-speed, low-power wireless data links using ions, positively or negatively charged atoms that are naturally available in the body
A fully rubbery stretchable diode maintains performance. Flexible devices can behave more like biological tissue, allowing for better bio-integrated devices. An example may be a soft patch device that could be implanted on the heart
Tiotronik’s Renamic Neo communicates with a medical device implanted in a patient, such as a pacemaker, ICD, or implantable cardiac monitor. The control unit received FDA premarket approval in April 2022. The privately owned medtech company has been developing medical devices that improve the quality of life of patients suffering from cardiovascular and endovascular diseases for more than 50 years
Atrial fibrillation — a form of irregular heartbeat, or arrhythmia — leads to more than 454,000 hospitalizations and nearly 160,000 deaths in the United States each year. Globally, it is estimated that approximately 60 million people are affected by the condition
Inside every cellphone lies a tiny mechanical heart, beating several billion times a second. These micromechanical resonators play an essential role in cellphone communication. Buffeted by the cacophony of radio frequencies in the airwaves, these resonators select just the right frequencies for transmitting and receiving signals between mobile devices
A novel software algorithm compatible with a wide range of smartwatches and fitness trackers detected irregular heart rhythms and accurately identified undiagnosed atrial fibrillation (AFib) 98 percent of the time, according to research presented at the American Heart Association’s Scientific Sessions 2021
A new artificial intelligence (AI) technology for heart imaging can potentially improve care for patients, allowing doctors to examine their hearts for scar tissue while eliminating the need for contrast injections required for traditional cardiovascular magnetic resonance imaging (CMR
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