Browse Topic: Digestive system
A small ultrasound sticker can monitor the stiffness of organs deep inside the body. The sticker, about the size of a postage stamp, can be worn on the skin and is designed to pick up on signs of disease, such as liver and kidney failure and the progression of solid tumors
Engineers at MIT and Caltech have demonstrated an ingestible sensor whose location can be monitored as it moves through the digestive tract, an advance that could help doctors more easily diagnose gastrointestinal motility disorders such as constipation, gastroesophageal reflux disease, and gastroparesis
Creaking joints come from cartilage rubbing on other soft tissue. A growling stomach signals hunger or that you’ve eaten something that disagrees with you. And though a cough can mean that you are ill, you might also be perfectly healthy and just took too big of a gulp of your drink. Even more interesting is that our body sounds and its variation over time could tell us a lot not only about a particular organ (e.g., your knee cartilage and tendons), but also about general wellness, and respiratory, cardiovascular, digestive, and neurological health. This article digs into the future of acoustic epidemiology and our growing ability to interpret the body’s sounds using artificial intelligence (AI
About 25 percent of the U.S. population suffers from fatty liver disease, a condition that can lead to fibrosis of the liver and, eventually, liver failure. Currently there is no easy way to diagnose either fatty liver disease or liver fibrosis. However, MIT engineers have now developed a diagnostic tool, based on nuclear magnetic resonance (NMR), that could be used to detect both of those conditions
Cancer immunotherapy, one of the most important and promising therapies for cancer treatments, is being used by oncologists to treat patients suffering from many different cancers including breast, cervical, colon, stomach, and skin
This SAE Aerospace Standard (AS) covers any protective system that serves the stated purpose
Objective: This study investigated the incidence of abdominal injuries in frontal crashes by occupant age and seating position. It determined the risk for abdominal injury (AIS 2+) by organ and injury source. Methods: 1997-2015 NASS-CDS was analyzed to estimate the occurrence of abdominal injuries in non-ejected, belted occupants involved in frontal crashes. Vehicles were included with 1997+ model year (MY). The annual incidence and rate for different types of abdominal injury were estimated with standard errors. The sources for abdominal injury were determined. Results: 77.8% of occupants were drivers, 16.7% were right-front passengers and 5.4% were rear passengers. Rear passengers accounted for 77.1% of 8-11 year old (yo) and 17.2% of 12-17 yo group. The risk for moderate abdominal injury (MAIS 2 + abdo) was 0.30% ± 0.053% in drivers, 0.32% ± 0.086% in right-front passengers and 0.38% ± 0.063% in rear occupants. The risk of MAIS 2 + abdo was highest at 0.76% ± 0.30% in the 60-84 yo
By combining engineered polymeric materials known as hydrogels with complex intestinal tissue known as organoids— made from human pluripotent stem cells — researchers have taken an important step toward creating a new technology for controlling the growth of these organoids and using them for treating wounds in the gut that can be caused by disorders such as inflammatory bowel disease (IBD
Surgeons can swab a patient’s exposed liver lightly on the surface with a special stylus, capturing the shape of the organ during surgery, and a computer can match that image with the CT scan on a screen. This GPS-like ability is far better than guessing where the tumor and vessels are by feeling for them, but even this road map can be off by centimeters and leaves surgeons guessing
Implanted medical devices such as left ventricular-assist devices for patients with heart failure or other support systems for patients with respiratory, liver, or other end organ disease save lives every day. However, bacteria that form infectious biofilms on those devices, called device-associated infections, not only often sabotage their success but also contribute to the rampant increase in antibiotic resistance currently seen in hospitals
A protocol based on ultrafast ultrasound imaging was applied to study the in situ motion of the liver while the abdomen was subjected to compressive loading at 3 m/s by a hemispherical impactor or a seatbelt. The loading was applied to various locations between the lower abdomen and the mid thorax while feature points inside the liver were followed on the ultrasound movie (2000 frames per second). Based on tests performed on five post mortem human surrogates (including four tested in the current study), trends were found between the loading location and feature point trajectory parameters such as the initial angle of motion or the peak displacement in the direction of impact. The impactor tests were then simulated using the GHBMC M50 human body model that was globally scaled to the dimensions of each surrogate. Some of the experimental trends observed could be reproduced in the simulations (e.g. initial angle) while others differed more widely (e.g. final caudal motion). The causes for
Past studies have found that a pressure based injury risk function was the best predictor of liver injuries due to blunt impacts. In an effort to expand upon these findings, this study investigated the biomechanical responses of the abdomen of post mortem human surrogates (PMHS) to high-speed seatbelt loading and developed external response targets in conjunction with proposing an abdominal injury criterion. A total of seven unembalmed PMHS, with an average mass and stature of 71 kg and 174 cm respectively were subjected to belt loading using a seatbelt pull mechanism, with the PMHS seated upright in a free-back configuration. A pneumatic piston pulled a seatbelt into the abdomen at the level of the umbilicus with a nominal peak penetration speed of 4.0 m/s. Pressure transducers were placed in the re-pressurized abdominal vasculature, including the inferior vena cava (IVC) and abdominal aorta, to measure internal pressure variation during the event. Jejunum tear, colon hemorrhage
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