Although progress has recently been made to characterise the transition of microscopic liquid fuel droplets from classical evaporation to a diffusive mixing regime, still little is known about the transition from one to the other under reactive conditions. The lack of experimental data for microscopic droplets at realistic operating conditions impedes the development of phenomenological and numerical models for droplet mixing, ignition, combustion and soot formation. In order to address this issue we performed systematic measurements using high- speed long-distance microscopy, for n-dodecane into gas at elevated temperatures (from 750 to 1,600 K) and pressures up to 13 MPa. We describe these high- speed visualizations at the microscopic level, including the time evolution of the liquid droplets, reaction wave, and soot distribution. Our measurements show that these parameters are influenced by the operating conditions (gas pressure, gas temperature, oxygen content) as well as the physical properties of the fuel.