Electrification is getting more important in the aviation industry with the increasing need for reducing emissions of carbon dioxide and fuel consumption. It is crucial to assess the behavior of Li-Ion batteries at high-altitude conditions to design safe and reliable battery packs. This paper aims at benchmarking the performance of different formats of battery cells (pouch cells and cylindrical cells) in low-pressure environments. A test setup was designed and fabricated to replicate the standard procedure defined by the RTCA DO-311 standard, such as the altitude test and rapid decompression test. During the test voltage, current, temperature, and pressure were monitored, and the evaluation criteria is based on the capacity retention, along with the structural integrity of the cell. From preliminary tests, it was observed that cylindrical cells do not show a significant change in performance at low-pressure conditions thanks to their steel casing. Failure has been observed in pouch cells due to the absence of a rigid enclosure.