The Role of Chemically Modified Surfaces in the Construction of Miniaturized Analytical Instrumentation

This paper describes the development of a thin-film optical sensor for measuring pH. The indicator behaves as a polyprotic acid with differing optical properties in each of its chemical forms. Together, these properties facilitate the development of an internally calibrated sensor by calculating the ratios of the absorption maximas for each form of the indicator. The covalent immobilization procedure developed demonstrated long term stability of 4 months without recalibration.