In order to solve the problem of low bus load factors due to the inefficiency of transferring passengers between the high-speed rail station and regular bus networks (to contribute to the development of integrated urban transport), the present research is focused on Guigang Station. It explores the existing transfer scenario, including its inadequacies, using field studies, statistical data, non-parametric data, and simulation models with AnyLogic. Solutions are recommended in three aspects, which include facilities, timing, and congestion management with the help of AnyLogic simulation. The results show that after optimization, the mean rate of occupancy of Bus Route 304 went up by 0.173–0.261, and the average total transfer time was reduced by 75.25 seconds. Moreover, the density of passengers inside congested areas A and B near the station entrances was greatly minimized. The present study offers a benchmark on how the transfer system can be optimized at high-speed railway stations in smaller and mid-sized city settings.