In expressway reconstruction and extension projects, median opening sections are safety bottlenecks and high-congestion areas. Decision-making for their speed limit schemes must balance multiple conflicting objectives, such as safety, efficiency, economy, and driver psychology, which traditional single-objective methods cannot adequately address. This study proposes a Multi-Criteria Decision-Making (MCDM) framework based on the Fuzzy Analytic Hierarchy Process (FAHP). First, three speed limit schemes were designed based on standards and investigations. Subsequently, a comprehensive evaluation hierarchy including six main criteria and 21 sub-criteria was constructed. Finally, expert questionnaires were used to acquire the weights and score the schemes. The results show that “Safety” is the dominant criterion with the highest weight, reaching 54.3%. Scheme 3 (the 80→70 km/h scheme) achieved the highest comprehensive score, as it realized the best balance across dimensions such as efficiency, economy, and driver acceptance. Sensitivity analysis verified the robustness of this ranking result. The FAHP framework proposed in this study provides a scientific and robust tool for speed limit decision-making in complex work zones.