The transition to software-defined vehicles (SDVs) necessitates a paradigm shift in both control strategies and vehicle architecture. The EU-funded R&D project SmartCorners addresses this challenge by developing integrated, modular, and scalable smart corner systems (SCS) that combine in-wheel motor (IWM)-based propulsion, brake blending, active suspension system, and steer-by-wire functionality in one module. These SCS can be retrofit or smoothly integrated into the highly adaptable skateboard chassis architecture of modern electric vehicles (EVs), enabling scalable deployment across diverse vehicle types. The central approach of this paper is the utilization of artificial intelligence (AI) and machine learning (ML) to implement multi-layer, data-driven control strategies, facilitating real-time actuation, fault mitigation, and user-centric EV architecture. The SmartCorners project strives to demonstrate significant enhancements, including improved real-world driving range due to enhanced energy-efficiency, reduced component and system costs, and a cut-down in development time of EVs, enabled by digital-twin-based design methodologies. Beyond these performance gains, SmartCorners establishes the foundational principles of modularity, adaptability, and software integration that underpin the evolution toward SDVs. The role of thermal and cabin comfort control is completely different for EVs and internal combustion engine vehicles, with the latter using waste heat from the combustion of fossil fuels for cabin heating, ventilation, and cooling (HVAC). In EVs the required energy is directly taken from the traction battery and precise thermal and cabin comfort control affecting essential components of the vehicle but also the user-perceived driving experience. These project achievements highlight a critical bridge between innovation and electrification on component-level, and the holistic software-defined mobility systems of the future.