Low carbon, though poorly igniting (i.e., low cetane) fuels, such as methanol, ethanol, and ammonia, are gaining momentum in the maritime fuel market. The most adopted strategy to address the fact that these fuels will not, under typical two-stroke marine engine conditions, auto-ignite, is to co-inject a pilot fuel, such as (very) low sulfur marine fuel oil, which does auto-ignite and furthermore doubles as a spark of sorts for the poorly igniting base fuel. This so-called dual-fuel approach is costly and cumbersome. Cetane boosters are known to improve ignitability of alcohol fuels to the point that a pilot fuel is no longer required. In our earlier research, we found some indication that lignin model compounds could likewise improve the ignitability of alcohols. This paper builds further on this hypothesis, now using commercially available lignin rather than model compounds. Auto-ignition behavior of methanol and ethanol was investigated with up to 10 wt% of therein solubilized lignin in both an Advanced Fuel Ignition Delay Analyzer (AFIDA) and (two-stroke) spray combustion chamber. The results suggest that lignin indeed improves the ignitability of both alcohols and that pilotless auto-ignition is possible under realistic two-stroke marine engine conditions when 10% of (alcohol-soluble) lignin is blended into ethanol, with the associated cetane number being close to 10.