In April 2025, the International Maritime Organization (IMO) held the 83rd session of the Marine Environment Protection Committee (MEPC) in London, the United Kingdom. During this crucial meeting, extensive discussions and in-depth negotiations were carried out regarding the mid-term greenhouse gas (GHG) reduction measures under the newly proposed Net-Zero Framework (NZF). The NZF establishes a medium-term regulatory framework featuring a dual compliance structure consisting of basic and direct compliance. Its core components include the Greenhouse Gas Fuel Standard (GFS), the Greenhouse Gas Emissions Pricing (GEP), and Flexible Compliance (FC). Among these, the GFS is positioned as the core regulatory instrument, given that it directly governs the carbon intensity of marine fuels, thereby providing the foundational driver for the industry's transition towards zero or near-zero fuels and technologies (ZNZs). The implementation of this framework will systematically restructure the entire industrial chain of international shipping, including marine power system research and development, new-type ship design and construction, green fuel production, storage, supply, bunkering and certification, seafarers' professional training, as well as daily shipping operation and management. It will inevitably bring about profound and far-reaching impacts on the technological route, investment layout, operational mode, and competitive landscape of the global maritime industry. Against this background, this paper focuses on the NZF, systematically clarifying its formulation background, core institutional components, and practical operational mechanisms. Taking an 86K bulk carrier as the research object, this study carries out a detailed case analysis to reveal the actual challenges and response pathways for shipowners and operating enterprises under the new regulatory system. On this basis, this paper further proposes targeted coping strategies and practical reference suggestions for the shipping industry to adapt to and comply with the upcoming NZF requirements, so as to provide decision support for the sustainable and low-carbon development of the maritime sector.