The integration of ergonomics and artificial intelligence (AI) in the automotive industry has the potential to revolutionize the way how vehicles are designed, manufactured and used. The aim of this article is to review the recent literature on the subject and discuss the opportunities and challenges presented by the integration of these two fields. The paper begins defining the ergonomics and the AI and providing an overview of their respective roles in the automotive industry. It then examines the benefits of the integration of ergonomics and AI in the automotive industry, including the optimization of vehicle design and manufacturing process. The enhancement of the driver experience, and improvement of safety accessibility, and customization, however, the integration of ergonomics and AI in the automotive industry also presents challenges, including ethical and legal considerations, data privacy, liability, and the impact on the employment in the automotive industry. The paper reviews research on these challenges and suggests that the development of international standards for the integration of AI in the vehicles may be necessary to ensure that AI systems in vehicle are secure, highlighting the need for future research to explore the integration of ergonomic and AI in the automotive industry. Future research should focus and addressing the ethical, legal, and societal implications of the AI in vehicles, as well as exploring new opportunities for the use of AI in design, manufacturing, and use of vehicles in overall, the integration of ergonomics and AI in the automotive industry has the potential to significantly improve the design and manufacturing of vehicles, as well as enhance the driving experience for users. However, the integration of these two fields also poses challenges that must be addressed, including ethical concerns, legal considerations, and the employment in the automotive industry. By working to overcome these challenges, we ensure that benefits of ergonomics and AI in the automotive industry are fully realized while minimizing their potential negative impacts.