Wheels and tires on vehicles, are often directly (or indirectly) involved in collisions with other vehicles or fixed objects. In this study, the effects of the pneumatic tire and rim, as it contributes to a dynamic collision, was isolated and studied. A total of 15 mounted tires of various common sizes were selected to conduct 35 dynamic impact tests into the flat face of an instrumented concrete barrier. The tires and rims used in the tests ranged from heavy truck, light truck, down to common passenger vehicle tires. Each of the 15 tires and rims were impact tested individually to failure in order to explore the dynamic response and performance of pneumatic tires in collisions. Of the 35 tests, 28 were conducted with a single tire and rim configuration and 7 tests were conducted simulating a dual truck tire configuration. It was determined that the coefficient of restitution for 22 of the tire impacts into the rigid flat faced barrier were remarkably similar, around 0.9 ± 0.1. Additionally, three full-scale impact tests were conducted using four heavy truck tires, mounted in parallel with offsets typical of dual tire spacing, to impact the front, rear, and side of a mid-size SUV. The coefficient of restitution ranged between 0.31-0.33 for all three impacts. The acceleration and integrated velocity pulses of those same three tests were also compared with previous published research of narrow frontal object impacts and found to have good correlation. These instrumented pneumatic tire and rim tests provide well-documented real-world type tests that can be used for future evaluation, comparison, or simulation of similar applicable type collision events. They also provide a foundational basis for future exploration of the role of the pneumatic tires directly involved in impacts.