River regulation engineering is pivotal for harmonizing flood resilience,
                    ecological integrity, and navigation efficiency in large alluvial systems,
                    particularly under intensified hydrological stressors. The Yangtze River, Asia’s
                    largest fluvial network, has experienced altered hydro-sedimentary regimes and
                    exacerbated channel instability due to cascade reservoir operations, demanding
                    adaptive strategies to stabilize dynamic reaches. This study investigates
                    hydrodynamic and flow distribution responses to integrated regulation measures
                    in the Chizhou Reach—a vulnerable alluvial segment characterized by severe bank
                    erosion, sedimentation-induced flow imbalances, and constrained floodplains.
                    Using a 1:500/1:100 scaled hydraulic model validated under flood and low-flow
                    conditions, we assess synergistic effects of dredging, submerged dams, and
                    flow-regulating groynes. Here we show that dredging the Wanchuanzhou right
                    branch increases its flow diversion ratio by 1.71% (annual average flow) to
                    4.57% (bankfull flow), redistributing velocities (0.1–0.35 m/s reduction in
                    dredged zones) and mitigating sedimentation. Submerged dams modulate
                    cross-sectional flow areas: a –5 m crest dam in the Xinglongzhou right branch
                    reduces discharge by 23.5%, while a –2 m dam in the Changshazhou left branch
                    elevates the middle branch’s diversion ratio by 2.01%. Flow-regulating groynes
                    enhance right-branch inflows by 0.54–0.75% through hydrodynamic redirection,
                    balancing systemic flow partitioning. Contrasting prior studies focused on
                    isolated interventions, our results reveal that multi-project integration
                    addresses both localized instability and basin-scale hydraulic reconfiguration.
                    These findings underscore the necessity of holistic engineering frameworks to
                    mitigate cascading impacts in regulated rivers. By linking localized measures to
                    basin-scale hydraulic stability, this study advances strategies for sustainable
                    river management in sediment-laden, anthropogenically altered systems.