As the only energy storage component in the internal combustion engine vehicles (ICEVs), the battery is lack of comprehensive supervision and effective protection. Excessive discharge or aging cannot be detected and dealt with, which may lead to damage of the battery, even startup failure of the vehicle. In this paper, a full protection and optimization management scheme of the battery is proposed, to achieve comprehensive protection of the battery and energy optimization. Firstly, power partitioning model of the battery is established to reveal the battery characteristics in different states, which divides the battery into several function zones. Then, based on the power partitioning model, over discharge protection and graded overcurrent protection method are proposed, to achieve full protection of the battery. Thirdly, energy optimization management strategy based on generator’s multimode operation is introduced. Finally, to verify the validity and feasibility of the proposed method, tests are performed on the vehicle and test bench. The results reveal that overcurrent protection and over discharge protection of the battery is achieved, and the vehicle start-up capability is assured. In the meanwhile, the optimized energy consumption is able to be realized with the proposed method.