To face the current challenges of the automotive industry, there is a need for computational models capable to simulate the engine behavior under low-temperature and low-pressure conditions. Internal combustion engines are complex and have interconnected systems where many processes take place and influence each other. Thus, a global approach to engine simulation is suitable to study the entire engine performance. The circuits that distribute the hydraulic fluids -liquid fuels, coolants and lubricants- are critical subsystems of the engine. This work presents a 0D model which was developed and set up to make possible the simulation of hydraulic circuits in a global engine model. The model is capable of simulating flow and pressure distributions as well as heat transfer processes in a circuit. After its development, the thermo-hydraulic model was implemented in a physical based engine model called Virtual Engine Model (VEMOD), which takes into account all the relevant relations among subsystems. In the present paper, the thermo-hydraulic model is described and then it is used to simulate oil and coolant circuits of a diesel engine. The objective of the work is to validate the model under steady-state and transient operation, with focus on the thermal evolution of oil and coolant. For validation under steady-state conditions, 22 operating points were measured and simulated, some of them in cold environment. In general, good agreement was obtained between simulation and experiments. Next, the WLTP driving cycle was simulated starting from warmed-up conditions and from ambient temperature. Results were compared with the experiment, showing that modeled trends were close to those experimentally measured. Thermal evolutions of oil and coolant were predicted with mean errors between 0.7 °C and 2.1 °C. In particular, the warm-up phase was satisfactorily modeled.