Vaccines Via Dental Floss

Researchers have developed a novel vaccine delivery approach that uses dental floss to administer vaccines through the junctional epithelium, the thin, permeable tissue located between the teeth and gums. Unlike most epithelial tissues, this mucosal layer lacks a strong barrier, allowing immune cells to move freely and making it a promising entry point for immunization. Because many pathogens enter the body through mucosal surfaces such as the nose and lungs, stimulating antibody production at these sites can strengthen early immune defense.