Understanding Sensitivity in sCMOS Microscopy Cameras

The first sCMOS (scientific Complementary Metal Oxide Semiconductor) cameras were introduced some 10 years ago and are now the dominant sensor technology used in microscopy imaging cameras. In recent years, a new generation of sCMOS camera models based on back-illuminated sCMOS sensors has appeared. This new iteration of sCMOS camera technology promises even higher sensitivity than prior designs, and therefore may displace previous generations of front-illuminated sCMOS cameras and further push EMCCD (Electron Multiplying Charge Coupled Device) cameras to more niche applications.