Systems for Dynamic Control of Growth of Protein Crystals

Computer-controlled laboratory apparatuses for real-time monitoring and control of the growth of protein crystals are undergoing development. By use of an apparatus of this type, one can monitor and control several parameters that affect the growth of protein crystals; these parameters include temperature, pH, ionic strength, concentration of solute, rate of change of concentration of solute, and possibly others. One can utilize the monitoring capabilities to make decisions on the basis of the measured parameters. One can utilize the control capabilities to effect precise control of growth; one can also start, stop, or reverse growth at will.