Paracellular Drug Delivery Through Baker’s Yeast Microcapsules

Oral mucosal drug delivery is an alternative method of systemic drug delivery that offers several advantages over both injectable and enteral methods. Since the oral mucosa is highly vascularised, drugs that are absorbed through the oral mucosa directly enter the systemic circulation, bypassing the gastrointestinal tract and first-pass metabolism in the liver. This avoids some of the problems typically experienced with traditional oral medication like analgesics that have to be absorbed by the lining of the stomach or the intestine, either of which they can irritate.