Novel Microneedle Array Enables Breakthrough Treatment

A research team has designed a new microneedle patch to offer a highly effective nonantibiotic approach for the treatment of skin infection. In brief, the design engineered with ultrasound-responsive zinc-based metal-organic framework (MOF) antibacterial nanoparticles promises pain-free delivery to treat bacterial infection on skin tissue and facilitate skin repair at the same time. The team was led by Prof. Kelvin Yeung Wai-kwok, department of orthopaedics and traumatology, School of Clinical Medicine, LKS Faculty of Medicine, University of Hong Kong (HKUMed). The novel microneedle is around 50 μm in diameter, similar to a typical hair. The findings have been published in Science Advances.