Microfluidics, Chromatography, and Atomic-Force Microscopy

TBMG-2666

03/01/2008

Abstract
Content

A Raman-and-atomic-force microscope (RAFM) has been shown to be capable of performing several liquid-transfer and sensory functions essential for the operation of a microfluidic “laboratory on a chip” that would be used to perform rapid, sensitive chromatographic and spectro-chemical analyses of unprecedentedly small quantities of liquids. The most novel aspect of this development lies in the exploitation of capillary and shear effects at the atomic-force-microscope (AFM) tip to produce shear-driven flow of liquids along open microchannels of a microfluidic device. The RAFM can also be used to perform such functions as imaging liquids in microchannels; removing liquid samples from channels for very sensitive, tip-localized spectrochemical analyses; measuring a quantity of liquid adhering to the tip; and dip-pen deposition from a chromatographic device.

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Citation
"Microfluidics, Chromatography, and Atomic-Force Microscopy," Mobility Engineering, March 1, 2008.
Additional Details
Publisher
Published
Mar 1, 2008
Product Code
TBMG-2666
Content Type
Magazine Article
Language
English