Implantable Microsystems for Anatomical Rewiring of Brain Circuitry

It has been demonstrated that after a stroke-like lesion in the cerebral cortex of non-human primates, the remaining intact tissue undergoes extensive neuro-physiological and neuroanatomical remodeling. The ability of cortical areas remote from the infarct to form new cortico-cortical connections over long distances between the frontal and parietal lobes has been demonstrated. It is likely that these novel connections play a role in functional recovery after cortical injury.