High-Resolution Anatomic and Elastographic Transrectal Ultrasound for Improved Diagnosis of Prostate Cancer

Prostate cancer screening generally uses the Pro state Spe cific Antigen (PSA) blood test, free-PSA testing, and Digital Rectal Exam ination (DRE). When the PSA is used, there exists a significant gray area in which cancers may be missed. Addition ally, DRE is practically limited to the detection of shallow (subcapsular) palpable abnormalities. Even systematic multi-core biopsy fails to detect clinically detectable cancers in up to 34% of men. Thus, there is compelling clinical interest in finding improved detection methods.