Electrochemical Sensors Based on Enzyme-Linked Immunosorbent Assay

Improvements in trace biological molecule detection can have significant impact on healthcare, food safety, and environmental safety industries. Detection of trace biological molecules can be critical to the diagnosis of early onset of diseases or infections. Researchers at NASA Ames Research Center developed an electrochemical, bead-based biological sensor based on Enzyme-Linked Immunosorbent Assay (ELISA) combining a magnetic concentration of signaling molecules and electrochemical amplification using wafer-scale fabrication of microelectrode arrays.