Biotic-Abiotic Interface Between the Body and an Artificial Limb

Because of its high mechanical properties, chemical stability, and biocompatibility, titanium is a commonly used material in dental and orthopedic applications. Its excellent biocompatibility allows titanium implants to be directly anchored to bone, or osseo-integrated. The conventional prosthetic replacement in amputees is a stump-socket design, which transfers forces through the prosthetic to an external contact point on the patient. Such a design results in non-uniform distribution of pressure, and can lead to pain, infection, and necrosis of the soft tissues at the point of contact.