Biomarker Sensor System and Method for Multi-Color Imaging and Processing of Single-Molecule Life Signatures

NASA’s Jet Propulsion Laboratory offers a method to manufacture biomarker sensor arrays with nanoscale resolution and active regions on the order of 1 micron by applying nanolithographic direct-write techniques to the fabrication of Silane chemistry sensors on a transparent substrate. This novel technology enables extremely fine patterns of detectors suitable for multicolor imaging of single-molecule samples at resolutions far below the diffraction limit. The extremely small size of these sensors allows for rapid, highly specific screening for hundreds of functionalities within a single, small, integrated microfluidics chip.