Magazine Article

Activating STAT3 Alpha for Promoting Healing of Neurons

TBMG-2722

04/01/2008

Abstract
Content

A method of promoting healing of injured or diseased neurons involves pharmacological activation of the STAT3 alpha protein. Usually, injured or diseased neurons heal incompletely or not at all for two reasons: (1) they are susceptible to apoptosis (cell death); and (2) they fail to engage in axogenesis — that is, they fail to re-extend their axons to their original targets (e.g., muscles or other neurons) because of insufficiency of compounds, denoted neurotrophic factors, needed to stimulate such extension. The present method (see figure) of treatment takes advantage of prior research findings to the effect that the STAT3 alpha protein has anti-apoptotic and pro-axogenic properties.

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Citation
"Activating STAT3 Alpha for Promoting Healing of Neurons," Mobility Engineering, April 1, 2008.
Additional Details
Publisher
Published
Apr 1, 2008
Product Code
TBMG-2722
Content Type
Magazine Article
Language
English