This content is not included in
your SAE MOBILUS subscription, or you are not logged in.
Brain Strain from Motion of Sparse Markers
Technical Paper
2019-22-0001
This content contains downloadable datasets
Annotation ability available
Sector:
Language:
English
Abstract
Brain strain secondary to head impact or inertial loading is closely associated
with pathologic observations in the brain. The only experimental brain strain
dataset under loadings close to traumatic levels was calculated by imposing the
experimentally measured motion of markers embedded in the brain to an auxiliary
model formed by triad elements (Hardy et al., 2007). However, fidelity of the calculated strain as well as the
suitability of using triad elements for three-dimensional (3D) strain estimation
remains to be verified. Therefore, this study proposes to use tetrahedron
elements as a new approach to estimate the brain strain. Fidelity of this
newly-proposed approach along with the previous triad-based approach is
evaluated with the aid of three independently-developed finite element (FE) head
models by numerically replicating the experimental impacts and strain estimation
procedures. Strain in the preselected brain elements obtained from the whole
head simulation exhibits good correlation with its tetra estimation and exceeds
its triad estimation, indicating that the tetra approach more accurately
estimates the strain in the preselected region. The newly calculated brain
strain curves using tetra elements provide better approximations for the 3D
experimental brain deformation and can be used for strain validation of FE
models of human head.
Recommended Content
Authors
- Zhou Zhou - Neuronic Engineering, KTH Royal Institute of Technology, Sto
- Xiaogai Li - Neuronic Engineering, KTH Royal Institute of Technology, Sto
- Svein Kleiven - Neuronic Engineering, KTH Royal Institute of Technology, Sto
- Warren N. Hardy - Virginia Tech-Wake Forest Center for Injury Biomechanics, Bl
Citation
Zhou, Z., Li, X., Kleiven, S., and Hardy, W., "Brain Strain from Motion of Sparse Markers," SAE Technical Paper 2019-22-0001, 2020, https://doi.org/10.4271/2019-22-0001.Data Sets - Support Documents
Title | Description | Download |
---|---|---|
Unnamed Dataset 1 | ||
Unnamed Dataset 2 | ||
Unnamed Dataset 3 |
Also In
References
- Aimedieu , P. , and Grebe , R. 2004 Tensile strength of cranial pia mater: preliminary results Journal of Neurosurgery 100 1 111 114
- Bain , A.C. , and Meaney , D.F. 2000 Tissue-level thresholds for axonal damage in an experimental model of central nervous system white matter injury Journal of Biomechanical Engineering 122 6 615 622
- Bayly , P. , Cohen , T. , Leister , E. , Ajo , D. , Leuthardt , E. , and Genin , G. 2005 Deformation of the human brain induced by mild acceleration Journal of Neurotrauma 22 8 845 856
- Bayly , P.V. , Clayton , E.H. , and Genin , G.M. 2012 Quantitative imaging methods for the development and validation of brain biomechanics models Annual Review of Biomedical Engineering 14 369 396
- Fahlstedt , M. , Depreitere , B. , Halldin , P. , Vander Sloten , J. , and Kleiven , S. 2015 Correlation between injury pattern and finite element analysis in biomechanical reconstructions of traumatic brain injuries Journal of Biomechanics 48 7 1331 1335
- Feng , Y. , Abney , T.M. , Okamoto , R.J. , Pless , R.B. , Genin , G.M. , and Bayly , P.V. 2010 Relative brain displacement and deformation during constrained mild frontal head impact Journal of the Royal Society Interface 7 53 1677 1688
- Fenton , T. , Cherry , J. , and Klassen , G. 1978 Transmural myocardial deformation in the canine left ventricular wall American Journal of Physiology-Heart and Circulatory Physiology 235 5 H523 H530
- Gennarelli , T. , Thibault , L. , Tipperman , R. , Tomei , G. , Sergot , R. , Brown , M. , Maxwell , W. , Graham , D. , Adams , J. , and Irvine , A. 1989 Axonal injury in the optic nerve: a model simulating diffuse axonal injury in the brain Journal of Neurosurgery 71 2 244 253
- Giordano , C. , and Kleiven , S. 2016 Development of an unbiased validation protocol to assess the biofidelity of finite element head models used in prediction of traumatic brain injury Stapp Car Crash Journal 60 363 471
- Gomez , A.D. , Knutsen , A. , Xing , F. , Chan , D. , Lu , Y.-C. , Pham , D. , Bayly , P.V. , and Prince , J.L. 2018 3D Measurements of Acceleration-Induced Brain Deformation via Harmonic Phase Analysis and Finite-Element Models
- Hardy , W.N. , Foster , C.D. , Mason , M.J. , Yang , K.H. , King , A.I. , and Tashman , S. 2001 Investigation of head injury mechanisms using neutral density technology and high-speed biplanar X-ray Stapp Car Crash Journal 45 337 368
- Hardy , W.N. , Mason , M.J. , Foster , C.D. , Shah , C.S. , Kopacz , J.M. , Yang , K.H. , King , A.I. , Bishop , J. , Bey , M. , and Anderst , W. 2007 A study of the response of the human cadaver head to impact Stapp Car Crash Journal 51 17 80
- Ho , J. , Zhou , Z. , Li , X. , and Kleiven , S. 2017 The peculiar properties of the falx and tentorium in brain injury biomechanics Journal of Biomechanics 60 243 247
- Horgan , T.J. , and Gilchrist , M.D. 2003 The creation of three-dimensional finite element models for simulating head impact biomechanics International Journal of Crashworthiness 8 4 353 366
- Hyder , A.A. , Wunderlich , C.A. , Puvanachandra , P. , Gururaj , G. , and Kobusingye , O.C. 2007 The impact of traumatic brain injuries: a global perspective Neuro Rehabilitation 22 5 341 353
- Kimpara , H. , Nakahira , Y. , Iwamoto , M. , Miki , K. , Ichihara , K. , Kawano, S.-i., and Taguchi, T. 2006 Investigation of anteroposterior head-neck responses during severe frontal impacts using a brain-spinal cord complex FE model Stapp Car Crash Journal 50 509 544
- Kindberg , K. , Karlsson , M. , Ingels , N. , and Criscione , J. 2007 Nonhomogeneous strain from sparse marker arrays for analysis of transmural myocardial mechanics Journal of Biomechanical Engineering 129 4 603 610
- Kleiven , S. 2007 Predictors for traumatic brain injuries evaluated through accident reconstructions Stapp Car Crash Journal 51 81 114
- Kleiven , S. , and Hardy , W.N. 2002 Correlation of an FE model of the human head with local brain motion-consequences for injury prediction Stapp Car Crash Journal 46 123 144
- Knutsen , A.K. , Magrath , E. , McEntee , J.E. , Xing , F. , Prince , J.L. , Bayly , P.V. , Butman , J.A. , and Pham , D.L. 2014 Improved measurement of brain deformation during mild head acceleration using a novel tagged MRI sequence Journal of Biomechanics 47 14 3475 3481
- Kolaczek , S. , Hewison , C. , Caterine , S. , Berardelli , R. , Beveridge , T. , Herman , B. , Hurtig , M. , Gordon , K. , and Getgood , A. 2019 3D strain in native medial meniscus is comparable to medial meniscus allograft transplant Knee Surgery, Sports Traumatology, Arthroscopy 27 2 349 353
- Kolaczek , S. , Hewison , C. , Caterine , S. , Ragbar , M. , Getgood , A. , and Gordon , K. 2016 Analysis of 3D strain in the human medial meniscus Journal of the Mechanical Behavior of Biomedical Materials 63 470 475
- Mao , H. , Zhang , L. , Jiang , B. , Genthikatti , V.V. , Jin , X. , Zhu , F. , Makwana , R. , Gill , A. , Jandir , G. , and Singh , A. 2013 Development of a finite element human head model partially validated with thirty five experimental cases Journal of Biomechanical Engineering 135 11 111002
- Margulies , S.S. , Thibault , L.E. , and Gennarelli , T.A. 1990 Physical model simulations of brain injury in the primate Journal of Biomechanics 23 8 823 836
- Meaney , D.F. , Smith , D.H. , Shreiber , D.I. , Bain , A.C. , Miller , R.T. , Ross , D.T. , and Gennarelli , T.A. 1995 Biomechanical analysis of experimental diffuse axonal injury Journal of Neurotrauma 12 4 689 694
- Morrison , B. , Cater , H.L. , Wang , C.C. , Thomas , F.C. , Hung , C.T. , Ateshian , G.A. , and Sundstrom , L.E. 2003 A tissue level tolerance criterion for living brain developed with an in vitro model of traumatic mechanical loading Stapp Car Crash Journal 47 93 105
- Průša , V. , Rajagopal , K. , and Saravanan , U. 2013 Fidelity of the estimation of the deformation gradient from data deduced from the motion of markers placed on a body that is subject to an inhomogeneous deformation field Journal of Biomechanical Engineering 135 8 081004
- Sabet , A.A. , Christoforou , E. , Zatlin , B. , Genin , G.M. , and Bayly , P.V. 2008 Deformation of the human brain induced by mild angular head acceleration Journal of Biomechanics 41 2 307 315
- Takhounts , E.G. , Ridella , S.A. , Hasija , V. , Tannous , R.E. , Campbell , J.Q. , Malone , D. , Danelson , K. , Stitzel , J. , Rowson , S. , and Duma , S. 2008 Investigation of traumatic brain injuries using the next generation of simulated injury monitor (SIMon) finite element head model Stapp Car Crash Journal 52 1 31
- Thibault , L.E. , Gennarelli , T.A. , Margulies , S.S. , Marcus , J. , and Eppinger , R. 1990 The strain dependent pathophysiological consequences of inertial loading on central nervous system tissue Proc. International Conference on the Biomechanics of Impacts 191 202
- Waldman , L.K. , Fung , Y. , and Covell , J.W. 1985 Transmural myocardial deformation in the canine left ventricle. Normal in vivo three-dimensional finite strains Circulation Research 57 1 152 163
- Van Noort , R. , Black , M. , Martin , T. , and Meanley , S. 1981 A study of the uniaxial mechanical properties of human dura mater preserved in glycerol Biomaterials 2 1 41 45
- Zhang , L. , Yang , K.H. , and King , A.I. 2001 Comparison of brain responses between frontal and lateral impacts by finite element modeling Journal of Neurotrauma 18 1 21 30
- Zhao , W. , Ruan , S. , and Ji , S. 2015 Brain pressure responses in translational head impact: a dimensional analysis and a further computational study Biomechanics and Modeling in Mechanobiology 14 4 753 766
- Zhou , Z. , Jiang , B. , Cao , L. , Zhu , F. , Mao , H. , and Yang , K.H. 2016 Numerical simulations of the 10-year-old head response in drop impacts and compression tests Computer Methods and Programs in Biomedicine 131 13 25
- Zhou , Z. , Li , X. , and Kleiven , S. 2019 Biomechanics of acute subdural hematoma in the elderly: A fluid-structure interaction study Journal of Neurotrauma 36 13 2099 2108
- Zhou , Z. , Li , X. , and Kleiven , S. 2019 Biomechanics of periventricular injury
- Zhou , Z. , Li , X. , and Kleiven , S. 2019 Fluid– structure interaction simulation of the brain–skull interface for acute subdural haematoma prediction Biomechanics and Modeling in Mechanobiology 18 1 155 173
- Zhou , Z. , Li , X. , Kleiven , S. , Shah , C.S. , and Hardy , W.N. 2018 A reanalysis of experimental brain strain data: implication for finite element head model validation Stapp Car Crash Journal 62 293 318
- Zou , H. , Schmiedeler , J.P. , and Hardy , W.N. 2007 Separating brain motion into rigid body displacement and deformation under low-severity impacts Journal of Biomechanics 40 6 1183 1191