High temperature ignition delays of 2-methyltetrahydrofuran(MTHF) were measured behind a reflected shock tube under conditions of pressures from 1.2 to 10 atm, temperatures from 1050 to 1800 K, equivalence ratios from 0.5 to 2.0, and fuel concentrations of 0.25%, 0.5% and 1.0% diluted in argon. Results showed that the ignition delay of MTHF decreases with the increase of pressure, temperature, fuel concentration and increases with equivalence ratio. The trend is less notable at higher fuel concentrations and equivalence ratios. Based on sensitivity and pathway analysis at pressure of 10 atm, fuel concentration of 1.0%, equivalence ratio of 1.0 and temperature of 1550K, it was found that the most sensitive reaction of MTHF at high temperature is H+O2=O+OH, and the main consumption way is fuel decomposition instead of H-abstraction. Finally, ignition delays of MTHF were compared with THF both on experimental and kinetic analyses, and MTHF has lower ignition delays than THF. To our knowledge, it is the first time to present the ignition delays of MTHF under these conditions.