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Critical Assessment of Health Studies on Diesel Exhaust
Technical Paper
2009-26-0012
ISSN: 0148-7191, e-ISSN: 2688-3627
Annotation ability available
Sector:
Event:
SIAT 2009
Language:
English
Abstract
Health studies on Diesel Exhaust (DE) have investigated emissions from older diesel engines and do not reflect the potential health effects from current new technology diesel engines. Epidemiological studies and extensive investigations in laboratory animals, have not conclusively demonstrated a causal relationship between DE exposure and lung cancer. Relatively high levels of Diesel Particulate Matter (DPM) can elicit a mild, transient inflammatory response in the lung. Animal studies reported variable and inconsistent inflammatory changes. Human studies at high DE exposures suggest possible thrombogenic and ischemic effects. Some findings in animals were suggestive of potential reproductive responses at very high DE exposures. Chronic inhalation exposures with animal species found no adverse effects at levels 10–30 times higher than ambient DE levels.
Topic
Citation
Hesterberg, T. and Bunn, W., "Critical Assessment of Health Studies on Diesel Exhaust," SAE Technical Paper 2009-26-0012, 2009, https://doi.org/10.4271/2009-26-0012.Also In
References
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- Hesterberg T. W., et al., “A Critical Assessment of Studies on the Carcinogenic Potential of Diesel Exhaust” Crit. Rev. Toxicol. 36 9 727 776
- Hesterberg, T.W., et al., “Carcinogenicity Studies of Diesel Engine Exhausts in Laboratory Animals: A Review of Past Studies and a Discussion of Future Research Needs” Crit. Rev. Toxicol. 35 5 379 411 2005
- Hesterberg, T. W., et al., “Non-Cancer Health Effects of Diesel Exhaust (DE): A Critical Assessment of Recent Human and Animal Toxicological Literature” Crit. Rev. Toxicol. 2008