This content is not included in your SAE MOBILUS subscription, or you are not logged in.
Potential Effects of Biogenic Compound Production on Human Health in Closed Life Support Systems
ISSN: 0148-7191, e-ISSN: 2688-3627
Published July 11, 2005 by SAE International in United States
Annotation ability available
Extended habitation of space may include the cultivation of plants for atmospheric regeneration, water purification and food production. Plants produce bioactive compounds that may be released into the atmosphere as volatile organic compounds (VOCs). VOCs are produced through a variety of plant processes and vary greatly in chemistry and quantity though a plants life cycle. These compounds include numerous biogenic species including alcohols, isoprene, monoterpines, acids, carbonyls, alkanes and alkenes. In a closed environment, VOCs may create a toxic environment for either humans or other plants. Human responses to biogenic compounds may include acute toxicity, chronic toxic toxicity, and allergenic effects. Chronic exposure to low concentrations of biogenic compounds, as might be common during extended space habitation missions, is largely unstudied and of particular interest. The objectives of this paper are to provide an overview of the salient issues regarding potential production of biogenic VOC's, to identify potential responses of humans to these compounds and to assess the overall risk of exposure using epidemiological methodologies. A series of monographs were developed for the most common biogenic VOC's produced for Advanced Life Support (ALS) candidate crops. The monographs describe the compounds, reported sources, SMAC or TLV exposure limit (if established), and reported human responses and toxicity levels. In addition, biogenic responses on plant production systems are reported, if known. Finally, an assessment of potential risk on long duration habitation missions is provided.
CitationLarrat, E., Stutte, G., and Wheeler, R., "Potential Effects of Biogenic Compound Production on Human Health in Closed Life Support Systems," SAE Technical Paper 2005-01-2772, 2005, https://doi.org/10.4271/2005-01-2772.
- Ferl, R. Wheeler R.M. Levine H.G. Paul A.L. 2002 Plants in space Current Opin. in Plant Biol. 5 258 263
- Stutte, G.W. Wheeler R.M. 1997 Accumulation and effects of volatile organic compounds in closed life support systems Adv. Space Res. 20 10 1913 1922
- Charron, C.S. Cantliffe D.J. Wheeler R.M. 1996 A system and methodology for the measurement of volatile organic compounds produced by hydroponic lettuce in a controlled environment J. Amer. Soc. Hort. Sci. 121 483 487
- Pichersky, E. Gershenzon, J. 2002 The formation and function of plant volatiles: perfumes for pollinator attraction and defense Curr. Opin. In Plant Biol. 5 237 243
- Monje, O. Stutte G.W. Goins G.D. Porterfield D.M. Bingham G.E. 2003 Farming in space: Environmental and biophysical concerns Adv. Space Res. 31 1 151 167
- NASA 1999 Spacecraft Maximum Allowable Concentrations for Airborne Contaminants 1999 NASA Technical Report JSC 20584
- Abeles, F.B. Morgan P.W. Saltveit M.E. 1992 Ethylene in plant biology 2nd Academic Press, Inc. San Diego, CA
- Batten, J.H. Peterson B.V. Berdis E. Wheeler R.M. 1993 Biomass Production Chamber analysis of wheat study NASA Technical Memorandum 109192
- Batten, J.H. Stutte G.W. Wheeler R.M. 1995 Effect of crop development on biogenic emissions from plant populations grown in a closed plant growth chambers Phytochemistry 39 1351 1357
- Batten, J.H. Stutte G.W. Wheeler R.M. 1996 Volatile organic compounds detected in the atmosphere of NASA's Biomass Production Chamber Adv. Space Res. 18 4 5 189 192
- Stutte, G.W. 1996 Nitrogen dynamics in the CELSS Breadboard Facility at Kennedy Space Center Life Support and Biosphere Sci. 3 67 74
- MAK 1988 Henschler D Occupational toxicants: Critical data evaluation for MAK values and classification of carcinogens 1 Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area Weinheim, VCH Verlagsgesellschaft mbH 301 312
- Kuiper-Goodman, T. Nawrot P.S. 1990 Solanine and chaconine World Health Organization Food Additive Series 30
- Fraser, P. Chilvers C. Beral V. Hill M.J. 1980 Nitrate and human cancer: a review of the evidence Int J Epidemiolog 9 1 3 9
- van Poppel, G. Verhoeven D.T. Verhagen H. Goldbohm R.A. 1999 Brassica vegetables and cancer prevention Epidemiology and mechanisms. Adv. Exp. Med. Biol. 472 159 68
- Sandstead, H.H. 1992 Fiber, phytates and mineral nutrition Nutr. Rev. 50 30 1
- Food and Agricultural Organization 1995 Food allergies Report of the technical consultation of the Food and Agricultural Organization of the United Nations Rome