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Significant Association Between White Matter Lesions and Traffic Involvements in Healthy Middle Ages
Published October 03, 2012 by Society of Automotive Engineers of Japan in Japan
The relationship between traffic involvement and brain MRI findings in 3435 automobile drivers, 1752 men and 1683 women, aged 35 to 64 years, was examined. White matter lesions except cerebral infarction, most common MRI findings in middle ages, were significantly associated with crash involvement at cross roads. White matter lesions had no association with the other types of traffic involvement. Multiple logistic regression analysis showed that the adjusted odds ratio to cross-road crashes was 3.31 (95% confidence interval; 2.30-4.76). The evidence must be useful to elucidation of a human factor mechanism in traffic involvement and contributory to ITS development for enjoying safe driving.