This content is not included in
your SAE MOBILUS subscription, or you are not logged in.
Concepts of Bioisolation for Life Sciences Research on Space Station Freedom
Annotation ability available
Sector:
Language:
English
Abstract
The Biological Flight Research Laboratory (BFRL) includes a large (approximately 2.5 meter) diameter centrifuge, biospecimen habitats, a microgravity habitat holding unit, a glovebox, a unit for the routine servicing of biospecimen chambers, and generic laboratory equipment. It is being designed to support non-human life sciences research on Space Station Freedom. To assure the health and welfare of biospecimens and flight crew, the BFRL must provide containment of particulate, microbial and potentially hazardous chemical substances as well as isolation of the inhabitant biospecimens from the cabin environment. There are currently no clear definitions within NASA of what constitutes a biological hazard or how such material should be contained and handled. This paper defines many of the risk concepts of concern to NASA and recommends requirements for the design and operation of life sciences spaceflight hardware and experiments. It concludes with a discussion of how these proposed requirements are being applied to the BFRL.
Authors
Topic
Citation
Funk, G. and Johnson, C., "Concepts of Bioisolation for Life Sciences Research on Space Station Freedom," SAE Technical Paper 911475, 1991, https://doi.org/10.4271/911475.Also In
References
- Bonting, S.L. Kishiyama J.S. Arno R.D. Facilities for Animal Research in Space with Special Reference to Space Station Freedom 20th Intersociety Conference on Environmental Systems Williamsburg, VA July 9-12 1990 SAE Technical Paper # 901303
- Arno, R.D. Horkachuck M.J. Research Centrifuge Accommodations on Space Station Freedom 20th Intersociety Conference on Environmental Systems Williamsburg, VA July 9-12 1990 SAE Technical Paper # 901304
- Johnson, C.C. Hargens A.R. Scientific Uses and Technical Implementation of a Variable Gravity Centrifuge on Space Station Freedom 20th Intersociety Conference on Environmental Systems Williamsburg, VA July 9-12 1990 SAE Technical Paper # 901360
- AIHA Biohazards Committee 1986 Biohazards Reference Manual American Industrial Hygiene Association Akron, OH
- Space Station Freedom Program Office, Reston, VA 1990 Payload Safety Requirements for Space Station Freedom Program Section 3.4 - Hazard Elimination and Control
- U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control National Institutes of Health 1988 Biosafety in Microbiological and Biomedical Laboratories First HHS Publication No. (CDC)88-8395
- Bonting, S.L. Arno R.D. Kishiyama J.S. Johnson C.C. Bioisolation on the Space Station 18th Intersociety Conference on Environmental Systems San Francisco, CA July 11-13 1988 SAE Technical Paper # 881050
- Ward-Dolkas, P. Schnepp T. Bioisolation Testing of Space Station Freedom Modular Habitats 19th Intersociety Conference on Environmental Systems San Diego, CA July 24-26 1989 SAE Technical Paper # 891516
- Savage, P.D., Jr. Jahns G.C. Dalton B.P. Hogan R.P. The Rodent Research Animal Holding Facility as a Barrier to Environmental Contamination 19th Intersociety Conference on Environmental Systems San Diego, CA July 24-26 1989 SAE Technical Paper # 891517
- Human Research Policy and Procedures Committee Johnson Space Center Houston, TX 1988 Human Research Policy and Procedures for Space Flight Investigations
- Synnestvedt, R. 1990 Centrifuge Facility Conceptual Study Vol. I Facility Overview and Habitats
- National Cancer Institute Office of Research Safety and Special Committee of Safety and Health Experts 1979 Laboratory Safety Monograph A Supplement to the NIH Guidelines for Recombinant DNA Research U.S. Dept. of Health, Education and Welfare Bethesda, MD
- Rethke, D.W. Steele J.W. Collection and Containment of Solid Human Waste for Space Station 20th Intersociety Conference on Environmental Systems Williamsburg, VA July 9-12 1990 SAE Technical Paper # 901304