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Exhaust Toxicological Profiles from Direct Injection Engine With and Without Diesel Particulate Filter Regeneration During NEDC Cycling
Technical Paper
2009-01-1090
ISSN: 0148-7191, e-ISSN: 2688-3627
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English
Abstract
European regulations have made the use of diesel particulate filter (DPF) unavoidable because all future diesel vehicles have to comply with the Euro 5 regulation regarding particulate matter emissions. Indeed, DPF has an overall excellent filtering efficiency but should be periodically regenerated. We propose here an in vitro comparative toxicological study of diluted sampled exhaust, emitted during legislative NEDC (New European Driving Cycle) cycles with or without a DPF regeneration phase. Pollutants, particle sizing, ESR (Electron Spin Resonance) measurement and post-exposure biological evaluation were monitored. Only TNFα (Tumor Necrosis Factor alpha), a biological molecule produced during inflammatory processes, was slightly induced for the highest exhaust concentration including regeneration phase. In conclusion, it appears that regeneration process does not induce an acute toxicity.
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Citation
Hasson, V., Morin, J., Preterre, D., Keravec, V. et al., "Exhaust Toxicological Profiles from Direct Injection Engine With and Without Diesel Particulate Filter Regeneration During NEDC Cycling," SAE Technical Paper 2009-01-1090, 2009, https://doi.org/10.4271/2009-01-1090.Also In
References
- von Klot S et al. Ambient air pollution is associated with increased risk of hospital cardiac readmissions of myocardial infarction survivors in five European cities Circulation 2005 112 20 3073 9
- Peters A et al. Exposure to traffic and the onset of myocardial infarction N Engl J Med. 2004 351 17 1721 30
- Mills NL et al. Ischemic and thrombotic effects of dilute diesel-exhaust inhalation in men with coronary heart disease N Engl J Med. 2007 357 11 1075 1082
- McCreanor J et al. Respiratory effects of exposure to diesel traffic in persons with asthma N Engl J Med. 2007 357 23 2348 58
- Morin JP Fouquet F Monteil C Le Prieur E Vaz E Dionnet F Development of a new in vitro system for continuous in vitro exposure of lung tissue to complex atmospheres: application to diesel exhaust toxicology Cell Biol Toxicol. 1999 Jun 15 3 143 52
- Le Prieur E Vaz E Bion A Dionnet F Morin JP Toxicity of diesel engine exhausts in an in vitro model of lung slices in biphasic organotypic culture: induction of a proinflammatory and apoptotic response Arch Toxicol. 2000 Oct 74 8 460 6
- Bion A Fall M Gouriou F Le Prieur E Dionnet F Morin JP Biphasic culture of rat lung slices for pharmacotoxicological evaluation of complex atmospheres Cell Biol Toxicol. 2002 18 5 301 14
- Morin JP Hasson V Fall M Papaioanou E Preterre D Gouriou F Keravec V Konstandopoulos A Dionnet F Prevalidation of in vitro continuous flow exposure systems as alternatives to in vivo inhalation safety evaluation experimentations: outcome from MAAPHRI-PCRD5 research program Exp Toxicol Pathol. 2008 Jun 60 2-3 195 205
- Park B Donaldson K Duffin R Tran L Kelly F Mudway I Morin JP Guest R Jenkinson P Samaras Z Giannouli M Kouridis H Martin P Hazard and risk assessment of a nanoparticulate cerium oxide-based diesel fuel additive - a case study Inhal Toxicol. 2008 Apr 20 6 547 66
- Bastien R Cochard P Method and device for determining the mass content of pollutants in a motor vehicle thermal engine exhaust gases http://www.wipo.int/pctdb/en/wo.jsp?IA=FR1998001289
- Mistry P Merazga Y Spargo DJ Riley PA McBrien DC The effects of cisplatin on the concentration of protein thiols and glutathione in the rat kidney Cancer Chemother Pharmacol 1991 28 4 277 282
- Crapo JD McCord JM Fridovich I Preparation and assay of superoxide dismutases Methods Enzymol 1978 53 382 93
- Wendel A Detoxification of drug metabolism; conjugaison and related system Jakoby B Glutathion Peroxydase In Methods in enzymology Academic press New York 77 325 333
- Aebi H Wyss SR Scherz B Skvaril F Heterogeneity of erythrocyte catalase II. Isolation and charaterization of normal and variant erythrocyte catalase and their subunits Eur J Biochem 1974 48 137 145
- Lowry OH Rosebrough NJ Farr AL Randal RJ Measurement with the Folin Phenol Reagent J Biol Chem 1951 193 1 265 275
- Kandylas IP Koltsakis GC NO2 Assisted Regeneration of Diesel Particulate Filters: A Modeling Study Industrial & Engineering Chemistry Research 41 9 April 24 2002
- Gouriou F Morin JP Weill ME On-road measurements of particle number concentrations and size distributions in urban and tunnel environments Atmospheric Environment 38 18 June 2004