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Parametric Study of Head Impact in the Infant
Technical Paper
2007-22-0001
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English
Abstract
Computer finite element model (FEM) simulations are often used as a substitute for human experimental head injury studies to enhance our understanding of injury mechanisms and develop prevention strategies. While numerous adult FEM of the head have been developed, there are relatively few pediatric FEM due to the paucity of material property data for children. Using radiological serial images of infants (<6wks old) and recent published material property data of infant skull and suture, we developed a FEM of the infant head to study skull fracture from occipital impacts. Here we determined the relative importance of brain material properties and anatomical variations in infant suture and scalp tissue on principal stress (σp) estimates in the skull of the model using parametric simulations of occipital impacts from 0.3m falls onto concrete. Decreasing the brain stiffness of pediatric brain tissue by a factor of two to simulate the softer adult brain properties we reported previously did not affect σp. Using adult brain stiffness reported by others (4 times higher than our pediatric values) increased σp in skull by 38%. Interestingly, the precision used to model compressibility of the brain (0.49-0.4999) significantly varied σp 30-77%, underscoring the influence of the brain properties in models of fracture in the highly deformable infant skullcase. Suture thickness, small anatomical variations in suture width and the exclusion of scalp did not affect σp of the skull; however, unusually large sutures (10 mm) in young infants significantly lowered σp. Validation of this model against published infant cadaver drop studies found good agreement with the prediction of fracture for falls onto hard surfaces. More biomechanical data from impacts onto softer surfaces is needed before skull fracture predictions can be made in these scenarios. In summary, the pediatric FEM response is not sensitive to small variations in anatomy or brain modulus, large deviations will significantly influence principal stress estimates and the prediction of skull fracture.
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Citation
Coats, B., Margulies, S., and Ji, S., "Parametric Study of Head Impact in the Infant," SAE Technical Paper 2007-22-0001, 2007, https://doi.org/10.4271/2007-22-0001.Also In
References
- Al-Bsharat A. Hardy W. Yang K. Khalil T. Tashman S. King A. 1999 Brain/skull relative displacement mognitude due to blunt head impact: new experimental data and model 43rd Stapp Car Crash Conference SAE San Diego, CA
- Bilston L. Liu Z. Phan-Thien N. 2001 Large strain behaviour of brain tissue in shear: some experimental data and differential constitutive model Biorheology 38
- Bylski D.I. Kriewall T.J. Akkas N. Akkas J.W. 1986 Mechanical behavior of fetal dura mater under large deformation biaxial tension Journal of Biomechanics 19 19 26
- Coats B. Margulies S.S. 2006 Material properties of human infant skull and suture at high rates Journal of Neurotrauma 23 1222 1232
- Crandall S. Dahl N. Lardner T. 1978 An Introduction to the Mechanics of Solids McGraw-Hill Singapore
- Crelin E.S. 1969 Anatomy of the newborn: an atlas Lea & Febiger Philadelphia
- DiMasi F. DiMasi F. DiMasi F. Eppinger R. Bandak F. 1995 Computational analysis of head impact response under car crash loadings 39th Stapp Car Crash Conference 425-438 San Diego, California
- Galford J. McElhaney J. 1970 A viscoelastic study of scalp, brain, and dura Journal of Biomechanics 3(2) 211 221
- Ji S. Margulies S.S. 2007 In vivo pons motion within the skull Journal of Biomechanics 40 92 99
- Kleiven S. von Holst H. 2002 Consequences of head size following trauma to the human head Journal of Biomechanics 35 153 160
- Klinich K. Hulbert G. Schneider L. 2002 Estimating infant head injury criteria and impact response using crash reconstruction and finite element modeling Stapp Car Crash Journal 46(November) 165 194
- Krabbel G. Appel H. 1995 Development of a finite element model of the human skull Journal of Neurotrauma 12 735 742
- Lapeer R.J. Prager R.W. 2001 Fetal head moulding: finite element analysis of a fetal skull subjected to uterine pressures during the first stage of labour Journal of Biomechanics 34 1125 1133
- 2004 The high frequency properties of brain tissue Biorheology 41 681
- Loyd A. Luck J. Buraglia N. Myers B. Frush D. Nightingale R. 2004 Thresholding techniques for developing geometrically accurate pediatric skull and cervical spine models Injury Biomechanics Research: Proceedings of the 32nd International Workshop 61-70 Nashville, TN
- McCracken P. Manduca A. Felmlee J. Ehman R. 2005 Mechanical transient-based magnetic resonance elastography Magnetic Resonance in Medicine 53 628 639
- McElhaney J.H. Fogle J.L. Melvin J.W. Haynes R.R. Roberts V.L. Alem N.M. 1970 Mechanical Properties of Cranial Bone J Biomech 3( 495 511
- McElhaney J.H. Melvin J.W. Roberts V.L. 1972 Dynamic characteristics of the tissues of the head 1972 Biomedical Engineering Conference Glasgow, Scotland
- McPherson G. Kriewall T. 1980a The elastic modulus of fetal cranial Bone: a first step toward understanding of the biomechanics of fetal head molding Journal of Biomechanics 13( 9 16
- Miller R. Margulies S. Leoni M. Nonaka M. Chen X. Smith D. Meaney D. 1998 Finite element modeling approaches for predicting injury in an experimental model of severe diffuse axonal injury. Proceedings of 42nd Stapp Car Crash Conference
- Prange M. Luck J. Dibb A. Van Ee C. Nightingale R. Myers B. 2004 Mechanical properties and anthropometry of the human infant head Stapp Car Crash Journal 48
- Prange M. Margulies S. 1999 Anisotropy and inhomegeneity of the mechanical properties of brain tissue at large deformation Prevention Through Biomechanics Novi, MI
- Prange M. Margulies S. 2002 Regional, directional, and age-dependent properties of brain undergoing large deformation Journal of Biomechanical Engineering 124
- Ruan J.S. Khalil T. King A.I. 1994 Dynamic response of the human head to impact by three-dimensional finite element analysis Journal of Biomechanical Engineering 116 44 50
- Shuck L. Advani S. 1972 Rheological response of human brain tissue in shear Journal of Basic Engineering 905 911
- Soboleski D. McCloskey D. Mussari B. Sauerbrei E. Clarke M. Fletcher A. 1997 Sonography of normal cranial suture AJR Am J Roentgenol 168 819 821
- Weber W. 1984 Experimental studies of skull fractures in infants] Z Rechtsmed 92 87 94
- Willinger R. Kang H.S. Diaw B. 1999 Three-dimensional human head finite-element model validation against two experimental impacts Ann Biomed Eng 27 403 410
- Young R. 1959 Age changes in thickness of scalp in white males Human Biology 31 74 79
- Zhang L. Hardy W. Omori K. Yang K. King A. 2001 Recent advances in brain injury research: a new model and new experimental data. Bioengineering Conference 831-832 The American Society of Mechanical Engineers Snowbird, UT