Tryptophan Fluorescence of Ocular Lens Protein for Early Diagnosis of Cataracts
TBMG-11327
10/01/2011
- Content
Cataracts are the leading cause of blindness worldwide; they affect more than 20 million people and result in ~1.3 million operations annually in the United States. Current methods of cataract detection are based on subjective observation of lens opacity by Rayleigh light scattering using a slit lamp. These methods are not sensitive enough to reveal structural changes on a molecular level; they can only reveal defects once their size becomes comparable with the optical wavelength (400-600 nm). This occurs at a very late stage of cataract development.
- Citation
- "Tryptophan Fluorescence of Ocular Lens Protein for Early Diagnosis of Cataracts," Mobility Engineering, October 1, 2011.