At The Boeing Company, the advent of a Determinant Assembly (DA) program and the subsequent production of accurate fuselage subpanels created a need to be able to position subpanels accurately and repeatably during fuselage assembly. The tool engineering organization of The Boeing Company and Advanced Integration Technology, Inc. (AIT) as the prime contractor, are developing and installing automated positioning and alignment systems throughout major 747 fuselage assembly areas which enable DA techniques. The benefits of this assembly approach and this automated precision tooling are flexibility, assembly accuracy, ease of assembly and associated speed, reduced downtime for tool maintenance, and improved shop-floor ergonomics.