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Cardiovascular Adaptation to O-G (Experiment 294): Instrumentation for Invasive and Non-invasive Studies
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English
Abstract
Many astronauts returning from space have difficulties regulating blood pressure, some to the point of fainting during quiet standing. Experiment 294 was designed to study this and other cardiovascular effects of adaptation to microgravity and to understand the mechanisms behind it. To accomplish this several cardiovascular variables had to be measured accurately. Heart rate, blood pressure, cardiac output (blood pumped by the heart each minute), stroke volume (blood pumped by the heart with each beat), limb flow, limb compliance, heart size and central venous pressure all had to been recorded during various stresses to understand fully the adaptation to space and the readaptation to earth's gravity. Numerous pieces of equipment were used. Some were purpose-built for the Spacelab mission and others were derived from commercial hardware. Developing spaceflight hardware is challenging and costly, but can lead to significant new information in the unique environment of space.
Authors
- Jay C. Buckey - University of Texas Southwestern Medical Center at Dallas
- Lynda D. Lane - University of Texas Southwestern Medical Center at Dallas
- Donald E. Watenpaugh
- Benjamin D. Levine - University of Texas Southwestern Medical Center at Dallas
- Willie E. Moore - University of Texas Southwestern Medical Center at Dallas
- F. Andrew Gaffney - University of Texas Southwestern Medical Center at Dallas
- C. Gunnar Blomqvist - University of Texas Southwestern Medical Center at Dallas
Citation
Buckey, J., Lane, L., Watenpaugh, D., Levine, B. et al., "Cardiovascular Adaptation to O-G (Experiment 294): Instrumentation for Invasive and Non-invasive Studies," SAE Technical Paper 911563, 1991, https://doi.org/10.4271/911563.Also In
References
- Buckey JC Goble RL Blomqvist CG A new device for continuous ambulatory central venous pressure measurement Medical Instrumentation 21 238 1987
- Buckey JC Watenpaugh DE Kim LT Smith ML Gaffney FA Blomqvist CG Initial experience with a new plethysmograph for zero-g use The Physiologist 28 S-145 1985
- Zoghbi WA Buckey JC Massey MA Blomqvist CG Determination of left ventricular volumes with use of a new nongeometric echocardiographic method: Clinical validation and potential application Journal of the American College of Cardiology 15 610 1990