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Effects on Man of 46-Day Life in a Confined Space at Normal Pressure
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English
Abstract
Six volunteers were selected and submitted at regular intervals throughout a 46-day control experiment in a climatic chamber to a large number of biological investigations (respiratory function, acid-base balance, circulatory function, biochemical determinations on blood and urine specimens) as well as psychomotor tests.
The results obtained clearly indicate that two kinds of adaptation occur:
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the first occurring during the first 2-3 days of confinement essentially marked by a significant increase of urinary volume and electrolyte output;
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the second, throughout the experiment mainly consists of a slight and progressive decrease of red blood cell count and plasma potassium.
Other parameter changes were well within range of the measuring technique's accuracy and physiological background; except for urinary calcium output which still remained elevated.
Finally, confinement failed to induce any significant degradation in psychomotor performances in spite of a sensation of fatigue.
Such a control experiment provides precise determination of the role played by confinement alone in the observed biological variations during submarine and space missions.
Authors
Citation
Radziszewski, E., "Effects on Man of 46-Day Life in a Confined Space at Normal Pressure," SAE Technical Paper 911533, 1991, https://doi.org/10.4271/911533.Also In
References
- GUILLERM R. RADZISZEWSKI. E. 1979 Effects on man of 30 day exposure to a Pi CO 2 of 14 torr (2 %): application to exposure limits Undersea. Biomed. Res. 591 594
- RADZISZEWSKI. E. 1987 2 Lyon, France 1 o 87 11
- RADZISZEWSKI E. GIACOMONI C. GUILLERM R. 1988 2 Proceedings Colloq. Space and Sea Marseille, France 1 19 23
- MOLINA CE. AIACHE J.M. BEDU M. MENAUT P. WAHL D. 1982 11 2325 2328
- BLACQUE BELAIR A. MATHIEU DE FOSSEY B. FOURESTIER M. 1980 MALOINE 1
- BOUR H. DEROT M. 1966 BAILLERE Paris 1
- APFELBAUM M. PERLEMUTER L. NILLUS P. FORAT C. BEGON M. 1981 Masson Paris 1
- SCHAEFER K.E 1979 Physiological stresses related to hypercapnia during patrols on submarines Undersea Biomed Res. 6
- SCHAEFER K.E ANDERSEN M.E BENNETT B HAMILTON R.W. HEDGEPETH C. 1976 Physiological and toxic effects of respiratory and contaminant gases (acute and chronic.) in National Plan for the safety and health of divers in their quest for subsea energy BECKETT Und. Med. Soc. Inc. Rockville Pick, USA 1 9.1 9.33
- LEONARD J.I WHITE R.J RUMMEL J.A 1985 Math modelling as a complement to the scientific inquiry of physiological adaptation to space flight: fluide, endocrine and circulatory regulation Proceedings of the 2nd Intern. Conf. Space Physiol Toulouse ESA SP-237 233 244
- RAMBAUT P.C. LEACH C.S. WHEDON G.D. 1978 A study of metabolic balance in crewmembers of Skylab IV Acta Astronautica 6 1313 1322
- PAK Z.P KOZYREVSKAYA G.I. KOLOSDOVA S. GRIGORYEV A.I 1973 Pecularities of water-mineral metalolism during 120 day hypokinesia Kosmicheskaya Biol. Med. 7 56 59
- DAVIES D.M LEITCH D.R MORRIS J.E.W GRAY S.P 1976 The effects on man of continous exposure to 0,5 % carbon dioxide IMM report Royal Navy GOSPORT, G.B. o 22 76
- GRIGORIEV A.I. 1989 Man in space flight Proceedings Intern. Conférence: The potential of space for medical progress Toulouse, France CNES 1 17
- DAVIES D.M. MORRIS J.E.W. 1979 Carbon dioxide and vitamin D, effects on calcium metabolism in nuclear submarines Undersea Biom. Res. 6 571 580
- DAVIES D.M EDMONSTONE W.H BISHOP A MORRIS J.E.W. 1978 Urinary mineral excretion in men on a long submarine patrol and the effects upon it of oral administration of vitamin D INM report Royal Navy Gosport, G.B. 26 78
- HINSENKAMP M BURNY F BOURGOIS R DONKERWOLCKE M. 1981 In vivo bone strain measurements: clinical results, animal experiments and a proposal for a study of bone demineralization in weightlessness Aviat Space Environ. Med. 52 95 103
- ISSEKUTZ B. BLIZZARD J.J. BIRKHEAD N.C. RODAHL K 1966 Effect of prolonged bed rest on urinary calcium output J. Appl. Physiol 21 1013 1020
- LUTZ J. FOU CHEN KASPER C.E 1987 Hypokinesia - induced negative net calcium balance reversed by weight-bearing exercise Aviat. Space Environ. Med. 58 308 314
- GIANETTA C.L. CASTLEBERRY H.B 1974 Influence of bedrest and hypercapnia upon urinary mineral excretion in man Aerospace Med. 45 750 754
- PILONCHERY G FINCK C. MINAIRE P MESSY P REVOL A. 1982 40 17 22
- ALEXANDRE C. 1985 Proceedings of the 2nd. International Conf. on Space Physiol Toulouse, France ESA-SP 237 45 51
- LOUSSOUARN M. 1980 o 879
- LEACH C.S. JOHNSON P.C. CINTRON N.M. 1985 The regulation of fluid and electrolyte metabolism in weightlessness Proceedings 2nd Intern. Conf. Space Physiol Toulouse, France ESA-SP 237 31 36
- SAVILOV A. MIKHAILOV V.M. GRIGORYEV A.I 1985 Relationship between cardiovascular functions and fluid electrolyte metabolism during antiorthostatic hypokinesia Proceedings 2nd Intern. Conf. Space Physiol Toulouse, France ESA.SP 237 181 185
- MESSIER A.A HEYDER, E. BRAITHWAITE W.R. McCLUGEAGE C. PECK A. SCHAEFER K.E. 1979 Calcium, magnesium and phosphorus metabolism and parathyroid-calcitonin function during prolonged exposure to elevated CO2 concentrations on submarines Undersea Biom. Res. 6
- BOURKOVSKAIA T.E. ILIOUKHIN A.V. 1980 14 5 50 54